Modern Chemistry And Applicationsopen Access
We need vitamin B and vitamin C every day for our growth, but if we take them in surplus/less amounts, our growth will be hampered. If these
vitamins are taken into our body in encapsulated form, body takes these
vitamins according to its requirements and the growth will be normal. Encapsulation of the
vitamins is very important to protect these important
biomolecules from external hazards, i.e., oxidation, sensitization, photolytic cleavage etc.; for the regulatory delivery of necessary amount of vitamin at the targeted site for a period of time efficiently and precisely and; to prevent overdose. In this work, encapsulation of β-cyclodextrin with two
vitamins namely, nicotinic acid and ascorbic acid in aqueous medium have been explored by reliable spectroscopic, physicochemical and calorimetric methods as stabilizer, carrier and regulatory releaser of the guest molecules. Stereochemical nature of the inclusion complexes has been explained by 2D
NMR spectroscopy. Surface tension and conductivity studies further support the inclusion process. Isothermal titration calorimetric studies have been performed to determine the stoichiometry, association constant and thermodynamic parameters with high accuracy. The outcomes reveal that there is a drop in ΔSO, which is overcome by higher negative value of ΔHO, making the overall inclusion process thermodynamically favorable. Hence, this exclusive study describes that the inclusion complexes can be used as controlled delivery systems in the field of modern biomedical sciences.
High Impact List of Articles
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A new simple and practical method for establish available chlorine
Nicolás Juan Carlos, Milanesio Romina Cintia Original Article: Analytical Chemistry: An Indian Journal
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A new simple and practical method for establish available chlorine
Nicolás Juan Carlos, Milanesio Romina Cintia Original Article: Analytical Chemistry: An Indian Journal
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A validated reversed phase HPLC assay for the determination of cetirizine in human plasma
Reem Al-Swayeh, Syed N.Alvi, Muhammad M.Hammami Original Article: Analytical Chemistry: An Indian Journal
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A validated reversed phase HPLC assay for the determination of cetirizine in human plasma
Reem Al-Swayeh, Syed N.Alvi, Muhammad M.Hammami Original Article: Analytical Chemistry: An Indian Journal
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Evaluation of content of â-sitosterol from stem bark and flowers of Salmalia malabarica collected from different regions
Sunita Shailajan, Manasi Yeragi Original Article: Analytical Chemistry: An Indian Journal
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Evaluation of content of â-sitosterol from stem bark and flowers of Salmalia malabarica collected from different regions
Sunita Shailajan, Manasi Yeragi Original Article: Analytical Chemistry: An Indian Journal
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A validated stability-indicating RP-HPLC assay method for amsacrine and its related substances
M.Lalitha Devi, K.B.Chandrasekhar, K.V.Surendranath, B.M.Rao, M.B.V.Narayana Original Article: Analytical Chemistry: An Indian Journal
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A validated stability-indicating RP-HPLC assay method for amsacrine and its related substances
M.Lalitha Devi, K.B.Chandrasekhar, K.V.Surendranath, B.M.Rao, M.B.V.Narayana Original Article: Analytical Chemistry: An Indian Journal
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Spectrophotometric determination of benzidine present in pure sample and in industrial effluents
M.A.Sathish, M.S.Yogendra Kumar,Mansour S.Abdul Galil, Mahadevaiah, B.Shyla, C.Vijaya Bhaskar, G.Nagendrappa Original Article: Analytical Chemistry: An Indian Journal
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Spectrophotometric determination of benzidine present in pure sample and in industrial effluents
M.A.Sathish, M.S.Yogendra Kumar,Mansour S.Abdul Galil, Mahadevaiah, B.Shyla, C.Vijaya Bhaskar, G.Nagendrappa Original Article: Analytical Chemistry: An Indian Journal
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