Immunogenicity

 Immunogenicity is that the ability of a far off substance, like an antigen, to impress an immune reaction within the body of a person's or other animal. In other words, immunogenicity is that the ability to induce a humoral and/or cell-mediated immune responses. Antigens must be perceived as non-self by the natural framework. Level of immunogenicity relies upon the level of strangeness for example The more noteworthy the phylogenetic separations between two species, the more prominent the auxiliary (and subsequently the antigenic) uniqueness between them. To increase the immunogenicity of DNA immunization using HIV and/or SIV antigens, genes encoding several cytokines were used. Granulocyte-macrophage colony-stimulating factor (GM-CSF) associated with DNA vaccines recruits dendritic cells to the site of vaccination and increases antigen presentation.