Short communication
, Volume: 10( 4)Synthesis of new structures of imidazolium salts on the rout to possible drugs
As result of the strongly basic character of heterocyclic carbenes 1, they react with Broenstedt acids and have consequently been used as selective deprotonation reagents. The 2H-imidazolium salts formed by this method are accessible by other routes, alkylation of 2H-imidazoles, cyclization reactions or from the thiones and nitric acid, and may be used as precursors in the synthesis of 1 through deprotonation.
Abstract
As result of the strongly basic character of heterocyclic carbenes 1, they react with Broenstedt acids and have consequently been used as selective deprotonation reagents. The 2H-imidazolium salts formed by this method are accessible by other routes, alkylation of 2H-imidazoles, cyclization reactions or from the thiones and nitric acid, and may be used as precursors in the synthesis of 1 through deprotonation.
