Abstract

Tributylammonium fluorochromate(TriBAFC): An efficient and mild oxidant for coupling of thiols to disulfides

Author(s): Shahriare Ghammamy, Mohammad K.Mohammadi

Various kinds of aliphatic and aromatic thiols are converted into the corresponding disulfides by tributylammonium fluorochromate in excellent yields. The reactions perform cleanly and controlled to stop at the disulfide stage without over-oxidation side products. Coupling of thiols to their corresponding disulfides studied in solution at room temperature and in solution undermicrowave radiation. The easy procedure, simple work-up, short reaction times, and excellent yields are another advantages of this reagent.