Abstract

Theoretical Study and Calculation of the Biochemical Coefficients of Synthetic Biodegradable PGA and PLA Polymers

Author(s): Mohammad Rizebandi*

Biodegradable polymers are a particular clas of polymer that breaks down after its intended purpose by bacterial decomposition process to result in natural byproducts such as gases carbon dioxide and Nitrogen, water, and inorganic salts. In this study, some of the physicochemical properties, such as the logarithm of calculated Octanol-Water Partitioning Coefficients (logKow), Total Biodegradation (TBd in mol/h and g/h), water solubility (Sw, mg.L-1/25ºC) and median lethal concentration 50 (LC50), were calculated for the biodegradable synthetic polymers Poly Glycolic Acid (PGA) and Poly Lactic Acid (PLA) with variable length of the polymers. The equations of the model could be utilized to extend for longer polymers of PGA and PLA. Another common term is Lethal Concentration 50 (LC50), which describes the amount of chemical inhaled by test animals that causes death in 50% of test animals used during a toxicity test study. The LD50 and LC50 values are then used to infer what dose is required to show a toxic effect on humans The coefficients and factors studied on these polymeric compounds indicate acceptable physical chemistry properties for measuring hydrophobic, toxicity and other important parameters of these compounds