Abstract
Synthesis of unsymmetrical triindolylmethanes as potent analgesic agents
Author(s): A.J.Yamuna, K.M.Mahadevan, P.V.Habbu, V.P.VaidyaVarious unsymmetrical triindolylmethanes were synthesized by multistep approach. In final step the targeted synthesis was carried out by the condensation of twomoles of simple indolewith previously prepared ethyl 3-formylindole- 2-caboxylates in presence of antimony trichloride as catalyst. The pharmacological screening of the obtained compounds was proved for their potent analgesic activity.
