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Abstract

Synthesis of novel 3-(4-methoxy benzene sulfonyl )-2-(1,3-benzodioxol-5-yl )-4-(substituted phenyl)-1,5-benzothiazepines

Author(s): Suresh Singh Chauhan, Y.C.Joshi, H.L.Singh, H.Sachdeva

An efficient synthesis of novel 2,3,4-trisubstituted 1,5-benzothiazepines (4a-f) incorporating 1,3-benzodioxol nucleus is described. Compound (4af) was synthesized by the reaction of substituted diketones (3a-f) with 2- aminothiophenol. Formation of compound (3a-f) was achived by the reaction of 4-methoxy benzene sulfonyl chloride (1) with substituted propane - 1-(1,3-benzodioxol-5-yl)-3-phenyl-1, 3-dione (2a-f). The structure of the compounds has been established by elemental, IR, 1H NMR, 13C NMR and Mass spectral analyses.


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Organic Chemistry: An Indian Journal received 565 citations as per Google Scholar report

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