Abstract

Synthesis of chiral shiff base: Ferrocene-conjugates of amino acid esters

Author(s): Zhang Yu-Mei, Liu Peng, Zhang Hong-Li

Two novel chiral ferrocene-conjugates of amino acid esters were designed and prepared by condensation with formylFerrocene and enantiomerically pure amino acid esters. The products were characterized by melting point determination, rotation determination, IR, element analysis and 1H-NMR. Esterification of amino acids using thionyl chloride results enantiomerically pure amino acid esters(L-Phenylalanine methyl ester and L-Leucine methylester).