Abstract
Synthesis of 2-(4ﾃｯﾂ?ﾂ｢-chlorophenyl)-6-methyl- 3-[1ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-aryl-2ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-prop-en-1ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-ones-3-yl] / (3 ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢ﾃ?ﾂ?aryl - 4ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢,5ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-dihydro-1ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-H-pyrazol-5ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-yl)/(3ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-arylisoxazole-5ﾃｯﾂ?ﾂ｢ﾃｯﾂ?ﾂ｢-yl) - imidazo[1,2-a]pyridine
Author(s): V.V.Bhuva, V.N.Patolia, A.U.Patel, D.M.Purohit2-(4ﾃδｯﾃや堙つ｢-chlorophenyl)-6-methyl-3-[1ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-aryl- 2ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-prop-en-1ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-ones-3-yl)-imidazol [1,2,-a]pyridines. (3a-31) ;2-(4'-chlorophenyl)-6-methyl-(3ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-aryl-4ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢,5ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢- dihydro-1ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-Hpyrazol-5ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-yl)imidazo[1,2a]pyridine(4a-41);2-(4'-chlorophenyl) -6-methyl-3-(3ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-arylisoxazole-5ﾃδｯﾃや堙つ｢ﾃδｯﾃや堙つ｢-yl)-imidazo [1,2-a]pyridine(5a-5l) have been synthesized. The products have been assayed for their biological activity againstGram+ve,Gramﾃ窶堙や砺e bacteria and fungi. Some of the products showed moderate activity in concentration 50ﾃδｯﾃつﾃつｭg. The structures of the products have been elucidated by IR, 1H NMR,Mass spectral data, elemental analysis and thin layer chromatography.
