Abstract

Synthesis, Characterization, Theoretical Studies and Bioactivity of Co(Ii), Ni(Ii), Cu(Ii), Pd(Ii), Pt(Iv) And Cd(Ii) Complexes With Bidentate 3-{[(Z)-1h-Pyrrol-3-Ylmethylidene]Amino}-2-Thioxoimidazolidin-4-One

Author(s): Rehab Am Al Hassani, Sallal Ah Abdullah, Abdul Jabar Kh. Atia and Sura K Ibrahim

Chelation complexes of Co(II), Ni(II), Cu(II), Pd(II), Pt(IV) and Cd(II) were synthesized with new heterocyclic ligand [3-{[(Z)-1H-pyrrol-3-ylmethylidene]amino}-2-thioxoimidazolidin-4-one]. This ligand was characterized by C.H.N.S analysis, FTIR, UV-Vis, 1H NMR, 13C NMR and mass spectral analysis ,the synthesized complexes were identified and their geometrical were suggested in solid state by using (FT-IR) and (UV-Vis) spectroscopy, elemental analysis (C.H.N.S), flame atomic absorption technique, in addition to magnetic susceptibility and conductivity measurements. Hyperchem-8 program has been used to predict structural geometries of ligand and their metal complexes. The electrostatic potential (Ep) of the ligand was calculated, furthermore the heat of formation (ΔHf ), binding energy ((ΔEb), vibration spectra and bond length for the ligand and its metal complexes were calculated by PM3 methods. The antimicrobial activity of the ligand and its complexes has been extensively studied in microorganisms such as Escherichia coli and Staphylococcus aureus and fungi Candida albicans and Aspergillus flavus.