Synthesis, characterization and microbial activity of 5-[1-(1,3-benzothiazol-2-ylsulfanyl)alkyl]-1,3,4-thiadiazole-2-(3H)-thione

Debojyoti Chakraborty; Sita Ram Sharma; Madhu Bala; L.K.Mishra

Organic Chemistry: An Indian Journal
ISSN (PRINT): 0974-7516

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Abstract

Synthesis, characterization and microbial activity of 5-[1-(1,3-benzothiazol-2-ylsulfanyl)alkyl]-1,3,4-thiadiazole-2-(3H)-thione

Author(s): Debojyoti Chakraborty, Sita Ram Sharma, Madhu Bala, L.K.Mishra

Anumber of benzothiazole-2-ylsulfanyl derivatives 2-(1,3-Benzothiazol-2- ylsulfanyl)alkanoylhydrazide (IA ÂÃ‚Â– IG) and 5-[1-(1,3-Benzothiazol-2- ylsulfanyl)alkyl]-1,3,4-thiadiazole-2-(3H) thione (IIA-IIG) have been synthesised from (1,3-Benzothiazol-2-ylsulfanyl)acetic acid. These compounds were synthesied and characterized from their F.T.I.R, and HNMR spectral studies. The compound (IIA to IIG) were screened for antibacterial activity and antifungal properties. The compound 2A-2G showed appreciable antifungal and antibacterial activity.