Abstract
Synthesis and evaluation of antimicrobial activity of novel and highly functionalized 5-imidazolinone derivatives
Author(s): Mahesh M.Savant, Akshay M.Pansuriya, Chirag V.Bhuva, Jayesh V.Padaliya, Hemendra H.Bhat, Yogesh T.NaliaparaA 4-acetamido-2-ethoxy benzoylhydrazine 2 obtained by reacting hydrazine hydrate with methyl 4-acetamido-2-ethoxy phenyl benzoate. Further, compound 2 was condensed with 4-aryliden-2-phenyl-5-oxozolinones 3 in the presence of dry pyridine to afforded new5-imidazolinone derivatives in good yield (75-80%). The structures of newly synthesized compounds were confirmed by IR, 1H NMR,Mass spectral studies and elemental analysis.All the synthesized compounds have been screened for antimicrobial activity.
