All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis and Characterisation of 7-(1H-Benzimidazol-2-yl)-5-(Substituted Phenyl) Pyrido [2, 3-D] Pyrimidin-4-Amine for their Biological Activity

Author(s): N. Maheswaran, M. Francis Saleshier, K. Mahalakshmi, V. Suresh Kannan, N. Parthiban and K. Ananda Reddy

A new series of 7-(1H-benzimidazol-2-yl)-5-(substituted phenyl) pyrido [2, 3-d] pyrimidin-4- amine (6a-h) were synthesized by reacting substituted cyanopyridine derivatives with formamide, formic acid and dimethyl formamide under reflux. The title compounds have been characterized by IR, 1H NMR and mass spectral data. The synthesized compounds were evaluated for their qualitative antibacterial and in vitro antioxidant activity by agar diffusion and DPPH methods, respectively. In general, the title compounds have shown mild to moderate antibacterial and antioxidant activity as well.


Share this       
Google Scholar citation report
Citations : 9398

International Journal of Chemical Sciences received 9398 citations as per Google Scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research
  • ICMJE

View More