Synthesis and biological evolution of 3-aryl-2- (2-chloro-6-iodoquinonlin-3�?�?yl)-4-thiazolidinones

B.Shah; R.C.Khunt; M.K.Shah

Organic Chemistry: An Indian Journal
ISSN (PRINT): 0974-7516

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Abstract

Synthesis and biological evolution of 3-aryl-2- (2-chloro-6-iodoquinonlin-3�?�?yl)-4-thiazolidinones

Author(s): B.Shah, R.C.Khunt, M.K.Shah

Thiazolidin-4-ones (3a-g) have been synthesized by the cyclocondesation at thioglycalic acid with N-aryl-2-chloro- 6-iodo quinonin-3-yl azomethine (2a-g) which in turn have prepared by the action of amines on 2-chloro-6-iodoquinoline- 3-charboxaldihyde1. The structure of the compound (2) and (3) have been confirmed from elemental analysis, further supported by IR, 1H NMR andMass Spectral data.All the products have been screened formtheir antimicrobial activity against severalmicrobe.