Abstract

Synthesis and Antimicrobial Activity of Fused Methyl Diimino Pyrido Pyrimido Pyrimido Derivatives

Author(s): Sambhaji P. Vartale, Nagesh D. Kalyankar and Nilesh K. Halikar

Novel heterocyclic compounds 9-methyl-13,14-di-imino pyrido [1,2- a ] pyrimido [5,6- e ] pyrimido[2,3- b ]benzothiazole and their 1/2/3/4-substuited derivatives (5a-h) have been synthesized by condensing 3-cyano-4-imino-2-(methylthio)-7-methyl-4 H -pyrido [1,2- a ] pyrimidine (3) with 2-amino 1/2/3/4-substituted benzothiazole (4) by refluxing with N, N'-dimethyl formamide (DMF) and catalytic amount of anhydrous potassium carbonate.