Abstract
Synthesis and antifungal activity of new series of compounds against Ascosphaera apis
Author(s): Kostecka Ma�¹gorzata, Niewiadomy AndrzejThe fungicidal compounds synthesized by us and applied in the studies are: 3,1-benzothiazine, variously substituted thioamides, N-heterocyclic carbothionyl derivatives and 2,5-disubstituted 1,3,4-thiadiazole. Depending on their structure their action can be oriented towards zoo- and geophylic fungi destroying crops and raw material of vegetation origin as well as pathogenic for animals and man. The compounds are characterized by differentiated mechanismofmolecular interactions in energetic cell processes and disubstituted 1,3,4-thiadiazole inhibiting squale epoxidase and squale accumulation seem to be an interesting group. Selective estimation of action of some compounds from individual groups against the strain Ascosphaera apis of the fungus isolated frominsects infected with calciferous mycosis was made.
