All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis and Antibacterial Activity of Mannich Bases of 3, 4-Dihydro-8-Methoxy-2H-1, 2, 4-Triazino[3, 4-b] Benzothiazole-3, 4-Dione

Author(s): S. P. Vartale, V. N. Bhosale, S. V. Khansole, P. A. Kulkarni and J. S. Jadhav

2-Hydrazino-6-methoxy benzothiazole (1) in methanol on reaction with diethyl oxalate in the presence of pyridine afforded 3, 4-dihydro-8-methoxy-2H-as-triazino[3, 4-b]-benzothiazole-3, 4-dione (2). The latter on further reaction with formaldehyde and different heteryl amines such as morpholine, pyrrolidine and pipyridine afforded Mannich bases (3,5). The newly synthesized compounds were subjected to evaluation for antibacterial activity.


Share this       
Google Scholar citation report
Citations : 9398

International Journal of Chemical Sciences received 9398 citations as per Google Scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research
  • ICMJE

View More