Abstract

Simultaneous Spectrophotometric Estimation of Telmisartan and Atorvastatin Calcium in Tablet Dosage Form

Author(s): D. Saraswathi, V. Niraimathi, J. Priyadharisini and A. Jerad Suresh

Three new simple, accurate and precise spectrophotometric methods have been developed for simultaneous determination of telmisartan and atorvastatin calcium in pharmaceutical dosage form. Method A and Method B involve the first and second order derivative method for simultaneous estimation of these two drugs. Method C involves the area under curve for first order derivative spectrum. Both the drugs obey the Beer’s law in the range 5-30 µg for atorvastatin calcium and 5-40 µg for telmisartan. The results of analysis have been validated statistically and by recovery studies.