All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Simultaneous Estimation of Cilostazol and Aspirin in Synthetic Mixture using HPTLC Method

Author(s): Jayesh V. Patel, C. N. Patel, P. U. Patel, Pankaj H. Prajapati, I. S. Anand and M. B. Patel

A high performance thin layer chromatography (HPTLC) method was developed and validated for quantitative determination of cilostazol and aspirin in synthetic mixture. The analysis was performed using a mobile phase composed of methanol : ethyl acetate : toluene : solvent ether (1:2:2:0.5). The calibration graphs were linear correlation coefficient (r) > 0.995 in the studied concentration range of 100 to 800 ng/mL for cilostazole and 75-600 ng/mL for aspirin for HPTLC. Relative standard deviation of all the parameters for intraday and interday precision is less than 2% (0.75-1.25) and the accuracy was greater than 98%. So the proposed method is precise and accurate and can be applied directly and easily to the cilostazol and aspirin in synthetic mixture


Share this       
Google Scholar citation report
Citations : 9398

International Journal of Chemical Sciences received 9398 citations as per Google Scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research
  • ICMJE

View More