Abstract
Simple and efficient methods to ziprasidone, an anti-psychotic drug substance
Author(s): Thatipalli Poornachander, Kaga Mukkanti, Yerra Anjaneyulu, Gade Srinivas Reddy, Bathula Srinivasulu, Ramesh Kumar, Bollikonda SatyanarayanaTwo simple and efficient methods for the preparation of 5-(2-(4-(1,2- benzisothiozole-3-yl) 1-piperazinyl) ethyl)-6-chloro-1,3-dihydro-2H-indole- 2-one, commonly known as ziprasidone (1), an anti-psychotic drug, using commercially viable reagents are reported with very good yield and quality.
