Abstract

Refractive Index, Molar Refraction and Polarizability of Ciprofloxacin Hydrochloride in Aqueous-Glycine Solutions

Author(s): S. D. Deosarkar, M. P. Pawar, P. D. Tawde and S. M. Deoraye

Density and refractive index of binary {ciprofloxacin + water} and ternary {ciprofloxacin + aqueous-glycine} mixtures were measured as a function of drug (0.001-0.029 mol·dm−3) and glycine (0.1, 0.25 and 0.45 mol·dm−3) concentration at 26oC. Molar refraction and polarizability of aqueous drug solutions was calculated from density and refractive index data. Polarizability effects with drug and glycine concentration have been studied.