Abstract

Phytochemical profile and comparative antimicrobial and wormicidal activity of ethanol and methanol extracts of Coscinium fenestratum Colebr. and Nardostachys jatamansi DC

Author(s): S.J.Sudharshan, A.Chinmaya, T.R.Prashith Kekuda, Syed Murthuza, M.L.Sujatha, Namitha C.Yadav, N.C.Vallesha

The present study was carried to investigate phytochemical profile, antimicrobial and wormicidal activity of ethanol and methanol extracts of Nardostachys jatamansi DC and Coscinium fenestratum Colebr obtained by Soxhlet extraction process. Agar well diffusion method was employed to check the efficacy of extracts against bacteria and fungi. Wormicidal activity was assessed by determining paralysis and death time in earthworm model. The solvent extracts of the selected plants showed the presence of various phytochemical groups.Amarked antibacterial activity was observed in case of C. fenestratum extracts followed by N. jatamansi. The extracts of N. jatamansi were found to inhibit test fungi tomore extent than C. fenestratum.Adose dependent wormicidal activity was observed. Among extracts tested, N. jatamansi was found to be more efficient in terms of its activity as compared to C. fenestratum. the antimicrobial and wormicidal activity of extracts could be mainly attributed to the presence of various phytoconstituents.