Abstract

New Spectrophotometric Method for the Determination of Desloratadine in Pharmaceutical Formulations

Author(s): Ch. Chandra Sekhar, U. Viplava Prasad and K. Naresh Kumar

An Economic, precise, accurate, sensitive and simple spectrophotometric method developed for the quantitative estimation of desloratadine in pharmaceutical formulations. The method was based on the formation of ferric chloride and potassium ferricyanide, which forms a coloured chromgen exhibit the absorbance at λmax 710 nm and obeyed Beer’s law in the concentration ranges 1-5 µg/mL. Spectrophotometric parameters were established for standardization of the method including statistical analysis of data. The method has been successfully extended to the Pharmaceutical formulations