Abstract
Multicomponent stereo and regioselective reactions of beta lactams in water: Click reaction
Author(s): Sandip S.Kshirsagar, Madhavi M.Mutha, Mayuri R.Shitre, Kamalkishor G.BahetiMulticomponent reaction in water was used to prepare a series of triazole substituted trans-beta-lactams from the corresponding trans-4-acetoxylactam, sodium azide, and alkynes via a Cu(I)-catalyzed click chemistry with base free. This highly stereo and regioselective procedure is simple, clean and efficient.
