All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Microwave assisted synthesis and characterization of some new triazole derivatives

Author(s): T.Vijay kumar, Amol Y.Ghodke, N.Kashinath, B.N.Poul

The reaction of 4-chlorobenzoic acid (1) with thiocarbohrdrazide (2) by fussionmethod to get 4-amino-5-(4-chlorophenyl)-4H-1,2,4-triazole-3-thiol (3). Treatment of compound (3) with various aromatic aldehydes in presence of dry benzene to yield 4-(benzylidene amino)-5-(4-chlorophenyl)- 4H-1,2,4-triazole-3-thiol (4a-e) respectively. which on reaction with acetyl chloride and triethylamine in presence of dry benzene afforded 1-[3-(4- chlorophenyl)-5-mercapto-4H-1,2,4-triazol-4-yl]-4-phenylazetidin-2-one (5a-e). The purity of the compounds was checked by TLC. All newly synthesized compounds were characterized on the basis of IR, 1HNMR, mass spectral data and elemental analysis.


Share this       
Google Scholar citation report
Citations : 565

Organic Chemistry: An Indian Journal received 565 citations as per Google Scholar report

Indexed In

  • CASS
  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Directory of Research Journal Indexing (DRJI)
  • Secret Search Engine Labs
  • ICMJE

View More

Flyer