Microwave Assisted Solvent Free Friedlander Synthesis of 1, 8-Naphthyridines

S. Ravich; ran; K. Subramania; R. Arunkumar

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International Journal of Chemical Sciences
ISSN: 0972-768X

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Abstract

Microwave Assisted Solvent Free Friedlander Synthesis of 1, 8-Naphthyridines

Author(s): S. Ravichandran, K. Subramania and R. Arunkumar

1, 4 - Diazabicyclo [2.2.2] octane (DABCO) catalyzed Friedlander condensation of 2- aminonicotinaldehyde (1) with carbonyl compounds containing 9-methylene group (2a-g) has been achieved in solvent – free condition under microwave irradiation to give 1, 8-naphthyridines (3a-g).