Microwave Assisted Rapid Synthesis of 3, 4-Dihydropyrimidine-2-(1H)-Ones/Thiones Using LSA as a Catalyst under Solvent Free Conditions

Sadhana N. Chamle; Manjusha V. Yadav; Ashok D. Sagar

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International Journal of Chemical Sciences
ISSN: 0972-768X

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Abstract

Microwave Assisted Rapid Synthesis of 3, 4-Dihydropyrimidine-2-(1H)-Ones/Thiones Using LSA as a Catalyst under Solvent Free Conditions

Author(s): Sadhana N. Chamle, Manjusha V. Yadav and Ashok D. Sagar

Lignin Sulphonic Acid (LSA) was found to be an efficient catalyst for the synthesis of 3, 4- dihydropyrimidin-2-(1H)-ones/thiones from the multicomponent condensation reaction of aromatic aldehyde, ethyl acetoacetate and urea / thiourea in solventfree condition on microwave at 180 W.