All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Method Development and Validation for Quantitative Analysis of Rupatadine Fumarate by Ultraviolet Spectrophotometry

Author(s): M. Shaiba, M. Sindhura, K. Raghavi and R. Prashanthi

A simple and sensitive UV spectrophotometric method for the determination of rupatadine fumarate in tablet dosage form has been developed. Beer’s law is obeyed in the concentration range of 2- 20 µg/mL of rupatadine fumarate. Spectroscopic determination was carried out at an absorption maximum of 263 nm for rupatadine fumarate using methanol as a solvent. In UV spectroscopic method, the linearity over concentration range of rupatadine fumarate was 2-20 µg/mL with correlation coefficient 0.999. The mean assay and recovery percentage was found to be 99.4% and 99.25%, respectively. The results of the analysis for the method have been validated statistically and by recovery studies. The results obtained with the proposed methods are in given limits. This method is extended for analysis of drug in pharmaceutical formulation.


Share this       
Google Scholar citation report
Citations : 9398

International Journal of Chemical Sciences received 9398 citations as per Google Scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research
  • ICMJE

View More