Abstract

In-vitro anti-cancer studies of Cinnamaldehyde on breast cancer cell line (MCF-7)

Author(s): Meena Vangalapati, Sree Satya Nandam, D.V.Surya Prakash

Cinnamaldehyde occurs naturally in the bark of Cinnamon tress and other species of the genus Cinnamomum like Camphor and Cassia. Cinnamon bark contains Cinnamaldehyde about 80-90%. Cinnamaldehyde showed many bioactivities including inhibition of cancer cell growth,Antidiabetic, anti-fungal, anti-bacterial activities etc. The present work aims that invitro anti-cancer activity of Cinnamaldehyde on Breast cancerMCF-7 cell lines by using MTT cell growth inhibition assay. The highest percentage inhibition of cancer cell lineswas found to be 32.3%at a dose of 200µg/ml.