Abstract
Investigation of solvent effect on antioxidant property of some flavonoids in water-methanolmixture
Author(s): HamidrezaMoallem, Iman Nasrollahi, EbrahimTalebi(IC50),were analyzed by employing theKamlet-Abbot-Taft (KAT)multiple- Flavonoids are considered useful for human health because they have antioxidant properties. In were studied in the two-component solvent watermethanol (50-90%v/v)at physiological pH and roomtemperature using the DPPH method. In this this work, the antioxidant properties of flavonoids such as chrysin, quercetin, and naringeninmethod, the ascorbic acid, which has extremely high antioxidant power, was used as the standard reference material. The effects of the solvent on antioxidant property, which is expressed as the concentration of flavonoids with 50% radical inhibition parameter equetion and Dimroth-Reichardt’s normalized polarity parameter using the multivariate linear regression (MLR)method. The results showed that by reducing the polarity of the solvent (increasing the organic component) increase the antioxidant properties of all used compounds.
