Abstract

In vitro antibacterial activity of Cadaba fruticosa and Solanum trilobatum on some common pathogenic organisms

Author(s): Ramasamy Maheswaran, Ganesan Kumar, Gani Sharmila Banu, Kartheek R.Balapala, Saad Al-Jassabi

Indian traditional medicinal plants are extensively used for healing the illness and most of the people seeking remedies and health approaches free from side effects caused by synthetic chemicals. Recently, considerable attention has been paid to utilize eco-friendly and biofriendly plantbased products for the prevention and cure of different human diseases. The present study deals with the antibacterial activity of various solvents like acetone, aqueous, benzene, butanol, chloroform and ethanol extract of Cadaba fruticosa L. (Capparaceae family) leaves (10mg/ml) and Solanum trilobatum (Solanaceae family) leaves (10mg/ml) were determined using disc diffusion method against some pathogenic organisms like Streptococcus pyogens, Staphylococcus aureus, Salmonella typhi, Proteus vulgaries, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus subtilis, and Escherichia coli. The plants exhibited significant broad-spectrum activity against Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa. These results were compared with results obtained using standard antibiotics, Chloramphenicol (30ìg/disc) and streptomycin (30ìg/disc), which served as reference for inhibition zone diameter.