Abstract
Highly efficient Cs2CO3-catalyzed conjugate hydrocyanation of �¡, �¢-unsaturated diesters and enones with acetone cyanohydrin
Author(s): Jiyi Guo, Yao-Feng Wang, Shaoxiang Wu, Muhammad Sohail, Qi Wang, Fu-Xue ChenAn efficient conjugate hydrocyanation of a wide range of á,â-unsaturated esters and enones with acetone cyanohydrin has been developed with excellent yields (85-99%) using Cs2CO3 as the catalyst. Mild reaction condition, low catalyst loading and short reaction time make this protocol much practical.
