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Abstract

Highly efficient Cs2CO3-catalyzed conjugate hydrocyanation of �?¡, �?¢-unsaturated diesters and enones with acetone cyanohydrin

Author(s): Jiyi Guo, Yao-Feng Wang, Shaoxiang Wu, Muhammad Sohail, Qi Wang, Fu-Xue Chen

An efficient conjugate hydrocyanation of a wide range of á,â-unsaturated esters and enones with acetone cyanohydrin has been developed with excellent yields (85-99%) using Cs2CO3 as the catalyst. Mild reaction condition, low catalyst loading and short reaction time make this protocol much practical.


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Organic Chemistry: An Indian Journal received 565 citations as per Google Scholar report

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