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Abstract

Glycosidation of some Pharmaceutically Active Compounds

Author(s): Shaikh Sirajuddin Nizami, Rizwana Razi and Zaheer Ahmed

Glycosidation studies of some insecticidal compounds and pharmaceutically active bases have been reported. The method involved the classical SN2 displacement of trifluoromethanesulfonyloxy group in a suitably protected glucose moiety (1) through a variety of insecticidal bases (2-4) and active bases (5-7), which afforded corresponding glycosides (8-13) in good yield. The difficulties which, sometimes, are encountered during displacement reactions in carbohydrates are absent. The method provides an easy access for the syntheses of these potential compounds.


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  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research
  • ICMJE

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