Abstract
Fast and highly efficient oxidative coupling of thiols by o-xylylene bis (triphenylphosphonium) dichromate under solvent-free conditions
Author(s): Ali Noorani, Ali Amoozadeh, Mahmood Tajbaksh, Yaser Kamel, Hassan Ghasemnejad-BosraA fast and efficient solid state method for the chemoselective room temperature oxidative coupling of thiols to afford their corresponding disulfides using o-xylylene bis (triphenylphosphonium) dichromate as reagent is described. The reaction was applicable to a variety of thiols for giving high yields after short reaction times. Comparison of time/yield ratios of this method with some of those reported in the literature shows the superiority of this reagent over others under these conditions.
