Abstract

Evaluation of in-vitro antioxidant activity of methanol extract of Asystasia gangetica (L).T (Chinese violet)

Author(s): N.V.L.Suvarchala Reddy, Sneha J.Anarthe, Raghavendra N.M.Gokaraju Rangaraju

The present investigation evaluates the antioxidant activity of methanolic extract of leaves of Asystasia gangetica (L).T. (Acanthaceae) in various in vitro models. Besides, total phenolic was tested using Folin Ciocalteau reagent was investigated by method given by Liu et al. The methanolic extract of Asystasia gangetica shown significant antioxidant activity (p<0.05). TheDPPHradical scavenging, nitric oxide scavenging and superoxide scavenging activity of methanolic extract have IC50 value 179.67, 33.43, 17.106 respectively.The effect ofmethanol extract on reducing power of the extract was studied according to the reaction of Fe+3 to Fe+2. The reducing power of the extract increased with the increasing amount of the concentration. The in vitro studies clearly indicate that the methanol extract of Asystasia gangetica has significant antioxidant activity.