Abstract

Enzymes of Halogenase for Synthesis Development

Author(s): Bella Hadid

Halogenase enzymes have evolved in nature to regioselectively halogenate a wide range of biosynthetic precursors, with the halogens added often having a major impact on the biological activity of the resulting natural products. Synthetic seeks to create non-natural bioactive tiny molecules for use in medicine and cosmetics. A similar conclusion has been obtained in the field of agrochemicals. Organic compounds can be considerably improved by halogens, allowing them to regulate biological targets selectively in vivo. As a result, halogens can now be found in a wide range of pharmaceuticals and agrochemicals. Halogenated organic compounds are also common synthesis intermediates, and they're particularly beneficial in metal catalyst cross-coupling processes.