Abstract
Derivative spectrophotometric estimation of azathioprine in bulk drug and pharmaceutical dosage forms
Author(s): Popat B.Mohite, Ramdas B.Pandhare, Shantaram G.Khanage, Vinayak K.Deshmukh, Sandip H.BodkheA simple, precise and economical spectrophotometric method have been developed for the estimation of Azathioprine in bulk and pharmaceutical formulations. Azathioprine shows a sharp peak at 301.0 nm in first order derivative spectrumwith n=1. The drugs follows Beer-LambertÂ’s lawin the concentration range of 2-20ïÂÂgmL-1 in both the methods. Result of the analysis was validated statistically and found to be satisfactory.
