Abstract

Comparative anthelmintic activity of leaves and stems of Clerodendron multiflorum (Verbenaceae) Linn.

Author(s): Sneha J.Anarthe, Rasika D.Bhalke, Kamesh R.Swami, Devi R.Nambiar

All the extracts from the leaves and stems of Clerodendron multiflorum (Verbenaceae) were investigated for their anthelmintic activity against Pheritima posthuma. Each extract was studied for their dose dependant activity (20mg/ml, 40mg/ml, 60mg/ml),which involved determination of the time of paralysis and time of death of the worms. The potency of extracts for the anthelmintic activity of stemand leaves ofClerodendronmultiflorum was found to be methanolic extract>pet ether extract >chloroform extract>acetone extract. The methanol extract of both the parts i.e. stem and leaves were found to be more active. The stems of Clerodendron multiflorumshowedmore potent activity as compare to leaves.Albendazole (20mg/ml) and distilled water were included in the assay as standard drug and control, respectively