Abstract

Anti-inflammatory and analgesic activity of Capparis zeylanica Linn.

Author(s): Mishra Manas Ranjan, Mishra Ashutosh, Pradhan Dusmanta Kumar, Pradhan Amiya Ranjan, Panda Ashok Kumar, Behera Rajani Kanta, Jha Shivesh

The present workwas undertaken to explore the analgesic and anti-inflammatory activity of Capparis zeylanica Linn. (Capparidaceae) methanolic extract ofwhole plant.Analgesic activitywas performed by using hot plate and tail immersionmethods.Anti-inflammatory effectwas analyzed by carrageenan induced pawedema method.Adose of 250 mg/kg and 500mg/kg C. zeylanica methanolic extract showed significantAnalgesic effects {(Hot plate, 7.571.17), (Tail immersion, 5.550.66)} and {(Hot plate, 7.971.33), (Tail immersion, 6.501.17)} respectively.Anti-inflammatory effect of 500 mg/kgmethanolic extract showed higher percentage of inhibition (21.42%) at 180 min in comparison to 250 mg/kg (18.5%) followed by standard Diclofenac sodium(22.28%).