Abstract

Antihyperglycemic effects of clitoria ternatea linn. Leaves in albino rats

Author(s): N.Gopal, V.S.Saravanan, S.Sengottuvelu

The aqueous extract of Clitoria ternatea Linn leaves were screened for its antihyperglycemic activity in streptozotocin induced and glucose induced diabetic rats in doses of 100, 250 and 500 mg/kg body weight.At a dose of 100 mg/kg (bw), aqueous leaf extract did not produce significant antihyperglycemic activity, however a doses of 250 mg/kg of Clitoria Ternatea leaf extracts significantly reduced the glucose levels in the blood as compared to the standard drug, chlorpropamide at the end of 2 hrs. Increase of the dose does not show any significant increase in the activity. Aqueous leaf extract of Clitoria Ternatea significantly reduced (p<0.001) the elevation of glucose in the glucose-induced diabetic rats at 1 hr. From the results, it is concluded that the acute dose of aqueous extract of Clitoria ternatea Linn leaves exhibits good antihyperglycemic activity.