Abstract

An study of coordination behavior and antibacterial activities of tetradentate2-((E)-1,5-dimethyl-2-phenyl-3-((E)-quinolin-8-methyl)-2,3-dihydro-1Hpyrazol-4-ylimino)methyl)phenolwithCu(II),Ni(II) andCo(II)metal

Author(s): Amit Rai, Ashish Kumar, Rupa Sirohi

Four Schiff basemetal complexes ofCu(II), Ni(II), Co(II) have been synthesized froma newtetradentate ligand, 2-((E)-1,5-dimethyl-2-phenyl-3-((E)- quinolin-8-methyl)-2,3-dihydro-1H-pyrazol-4-yliminomethyl phenol. The ligand and its complexes have been characterized on the basis of Elemental analysis, Electronic., I.R., 1H-NMR and 13CNMR spectral studies. On the basis of Electronic spectral studies, for Cu (II) complex, deformed tetrahedral, Co (II) complex, tetrahedral and Ni (II) complex octahedral geometry has been proposed. The in- vitro antimicrobial activity of the investigated compounds was tested against the bacteria such as Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and fungi Candida albicans and Rhizopus stolonifer. The data indicate that most of the metal complexes have higher antimicrobial activity than the free ligand.