A practical one-pot conversion of alcohols into homologous nitriles catalyzed by PEG 400 and sodium iodide

Yu-Qing Cao; Zhan Zhang; Yan-Xin Guo

Organic Chemistry: An Indian Journal
ISSN (PRINT): 0974-7516

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Abstract

A practical one-pot conversion of alcohols into homologous nitriles catalyzed by PEG 400 and sodium iodide

Author(s): Yu-Qing Cao*, Zhan Zhang, Yan-Xin Guo

Alcohols were converted into nitriles by one-pot reactions with trimethylchlorosilane and sodium cyanide catalyzed by PEG400 and sodiumiodide in dichloromethane in excellent yields.