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Abstract

A green solvent-free protocol for the synthesis of poly-substituted quinolines using 3-methyl-1-sulfonic acid imidazolium chloride {[Msim]Cl} as an efficient and homogeneous catalyst

Author(s): Abdolkarim Zare, Maria Merajoddin, Ahmad Reza Moosavi-Zare

An efficient, simple and clean protocol for the synthesis of poly-substituted quinolines from2-aminoaryl ketones and carbonyl compounds possessing a reactivemethylene group in the presence of catalytic amount of Brønsted acidic ionic liquid 3-methyl-1-sulfonic acid imidazoliumchloride {[Msim]Cl} is described (Friedländer protocol). Using this protocol, the products are produced in high yields and short reaction times.


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Citations : 565

Organic Chemistry: An Indian Journal received 565 citations as per Google Scholar report

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